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dc.contributor.authorTrujillo Vázquez, Jesús María
dc.contributor.authorTejera, Sara
dc.contributor.authorDorta, Rosa L. 
dc.date.accessioned2019-09-03T12:45:07Z
dc.date.available2019-09-03T12:45:07Z
dc.date.issued2016
dc.identifier.urihttps://riull.ull.es/xmlui/handle/915/15994
dc.description.abstractA variety of chiral mono- and di-1,4-disubstituted 1,2,3-triazoles were synthesized by CuAAC 'click chemistry' as model compounds and their spectroscopic properties characterized. The UV and CD study of these compounds showed that 4-substituted aryl triazoles give rise to moderate exciton CD curves, under either homo- or hetero-coupling. The direction of the electric transition moment of the non-symmetric chromophores was determined by conformational analysis and supported by NMR data. The signs of the Cotton effects of the CD spectra were in complete agreement with the determined directions of the electric transition moments of the chromophores. Therefore, 4-substituted aryl triazoles can be used for the determination of the absolute configuration of organic compounds. In addition, the 4–(4-bromo-phenyl)-1,2,3-triazole allows red-shifted chromophores to be obtained via Suzuki reactions, thus avoiding overlap with the substrate absorptionsen
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.relation.ispartofseriesTetrahedron: Asymmetry 27 (2016)
dc.rightsLicencia Creative Commons (Reconocimiento-No comercial-Sin obras derivadas 4.0 Internacional)
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es_ES
dc.titleStudy of Aryl Triazoles for Absolute Configuration Determination
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1016/j.tetasy.2016.07.008
dc.subject.keywordTriazoleses_ES


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Except where otherwise noted, this item's license is described as Licencia Creative Commons (Reconocimiento-No comercial-Sin obras derivadas 4.0 Internacional)