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Anti-idiotypic Immunotherapy in Follicular Lymphoma Patients
| dc.contributor.author | Barrios del Pino, Yvelise | |
| dc.contributor.author | Yáñez, Rosa | |
| dc.contributor.author | Ruiz, Elena | |
| dc.contributor.author | Cabrera, Rafael | |
| dc.contributor.author | Dı´az-Espada, Fernando | |
| dc.date.accessioned | 2023-12-19T21:07:26Z | |
| dc.date.available | 2023-12-19T21:07:26Z | |
| dc.date.issued | 2008 | |
| dc.identifier.issn | 1524-9557 | |
| dc.identifier.uri | http://riull.ull.es/xmlui/handle/915/34903 | |
| dc.description.abstract | A specific immune response against the individual idiotypic determinants of clonal immunoglobulins can be elicited in patients with B-cell malignancies. We analyze the clinical outcome and the presence of tumor cells in the blood of 8 patients with follicular lymphoma, vaccinated with autologous idiotype protein from their lymphoma cells. After a median follow-up of 90 months (range: 54 to 128), all patients, except 1, remain in complete clinical remission and 5 are in complete molecular remission. Our results suggest that idiotype vaccination induces long-lasting clinical and molecular remissions and constitutes a potential curative treatment in follicular lymphoma patients. © 2008 Lippincott Williams & Wilkins, Inc. | en |
| dc.format.mimetype | application/pdf | |
| dc.language.iso | en | |
| dc.relation.ispartofseries | Journal of Immunotherapy, 2008 v.31 n. 3, 310-312 | |
| dc.rights | Licencia Creative Commons (Reconocimiento-No comercial-Sin obras derivadas 4.0 Internacional) | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es_ES | |
| dc.title | Anti-idiotypic Immunotherapy in Follicular Lymphoma Patients | |
| dc.type | info:eu-repo/semantics/article | |
| dc.identifier.doi | https://doi.org/10.1097/CJI.0B013E31816A8116 | |
| dc.subject.keyword | Lymphoma immunotherapy | |
| dc.subject.keyword | Idiotypic vaccination | |
| dc.subject.keyword | Tumor vaccines |
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