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dc.contributor.advisor
dc.contributor.authorRodríguez Díaz, Rubí 
dc.contributor.authorBlanes Zamora, Raquel
dc.contributor.authorPaz Montelongo, Soraya  
dc.contributor.authorGómez Rodríguez, Jorge
dc.contributor.authorRodríguez Fiestas, Sonsoles
dc.contributor.authorGonzález Weller, Dailos
dc.contributor.authorGutiérrez, Ángel J.
dc.contributor.authorRubio, Carmen
dc.contributor.authorHardisson, Arturo
dc.contributor.authorNiebla Canelo, Daniel
dc.contributor.authorVega, Samuel
dc.contributor.authorGonzález Dávila, Enrique
dc.contributor.otherObstetricia y Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología y Medicina Legal y Forense y Parasitología
dc.date.accessioned2023-12-22T21:05:35Z
dc.date.available2023-12-22T21:05:35Z
dc.date.issued2023
dc.identifier.urihttp://riull.ull.es/xmlui/handle/915/34984
dc.description.abstractInfertility has become more common, with an increased exposure to toxic compounds including heavy metals (HM). Follicular fuid (FF) surrounds the developing oocyte in the ovary and can be analysed to assess metal content. The levels of twenty-two metals were measured in the FF of ninety-three females in a reproduction unit, and their infuence on assisted reproduction technique (ART), were examined. The metals were determined by optical emission spectrophotometry. Low values of copper, zinc, aluminium, and calcium favour polycystic ovary syndrome. The relationships between the number of oocytes and metals: iron (rs=0.303; p=0.003) and calcium (rs=−0.276; p=0.007) are signifcant, as well as between the number of mature oocytes with iron (rs=0.319; p=0.002), calcium (rs=−0.307; p=0.003) and sodium (rs=−0.215; p=0.039) and are near to signifcance in the case of aluminium (rs=−0.198; p=0.057). In the group with a fertilisation rate ≤ 75%, 36% of the women presented calcium >176.62 mg/kg compared to the group with a fertilisation rate ≥ 75% where this percentage was only 10% (p=0.011). An excess of iron and calcium reduces the good quality embryo rate, and an excess of potassium impairs the blastocyst rate. If potassium is above 237.18 mg/kg and calcium is below 147.32 mg/kg, these conditions favour embryo implantation. Pregnancy is infuenced by high potassium and low copper levels. Controlling exposure to toxic elements is recommended for all couples with reduced fertility or receiving an ART.
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.relation.ispartofseriesBiological Trace Element Research (2023) 201:5069–5082
dc.rightsLicencia Creative Commons (Reconocimiento-No comercial-Sin obras derivadas 4.0 Internacional)
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es_ES
dc.titleThe Infuence of Follicular Fluid Metals on Assisted Reproduction Outcome
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1007/s12011-023-03578-3
dc.subject.keywordMetalen
dc.subject.keywordFollicular fluiden
dc.subject.keywordEmbryo qualityen
dc.subject.keywordPregnancyen
dc.subject.keywordPolycystic ovary syndromeen


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Licencia Creative Commons (Reconocimiento-No comercial-Sin obras derivadas 4.0 Internacional)
Except where otherwise noted, this item's license is described as Licencia Creative Commons (Reconocimiento-No comercial-Sin obras derivadas 4.0 Internacional)