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dc.contributor.authorValenzuela Fernández, Agustín 
dc.contributor.authorArmas Rillo, Laura de
dc.contributor.authorValera, María Soledad
dc.contributor.authorMarrero Hernández, Sara 
dc.contributor.otherMedicina Física y Farmacología
dc.contributor.otherGrupo "Inmunología Celular y Viral".
dc.date.accessioned2024-01-15T21:06:03Z
dc.date.available2024-01-15T21:06:03Z
dc.date.issued2015
dc.identifier.urihttp://riull.ull.es/xmlui/handle/915/35324
dc.description.abstractViral replication and spreading are fundamental events in the viral life cycle, accounting for the assembly and egression of nascent virions, events that are directly associated with viral pathogenesis in target hosts. These processes occur in cellular compartments that are modified by specialized viral proteins, causing a rearrangement of different cell membranes in infected cells and affecting the ER, mitochondria, Golgi apparatus, vesicles and endosomes, as well as processes such as autophagic membrane flux. In fact, the activation or inhibition of membrane trafficking and other related activities are fundamental to ensure the adequate replication and spreading of certain viruses. In this review, data will be presented that support the key role of membrane dynamics in the viral cycle, especially in terms of the assembly, egression and infection processes. By defining how viruses orchestrate these events it will be possible to understand how they successfully complete their route of infection, establishing viral pathogenesis and provoking diseaseen
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.relation.ispartofseriesReviews in Medical Virology
dc.rightsLicencia Creative Commons (Reconocimiento-No comercial-Sin obras derivadas 4.0 Internacional)
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es_ES
dc.titleMembrane dynamics associated with viral infection.en
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1002/rmv.1872


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