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dc.contributor.authorRodríguez Díaz, Rubí Nieves
dc.contributor.authorBlanes Zamora, Raquel
dc.contributor.authorPaz Montelongo, Soraya  
dc.contributor.authorGómez Rodríguez, Jorge
dc.contributor.authorRodríguez Fiestas, Sonsoles
dc.contributor.authorGonzález Weller, Dailos 
dc.contributor.authorGutiérrez Fernández, Ángel J. 
dc.contributor.authorRubio Armendáriz, María del Carmen 
dc.contributor.authorHardisson de la Torre, Arturo 
dc.contributor.authorNiebla Canelo, Daniel
dc.contributor.authorAlejandro Vega, Samuel
dc.contributor.authorGonzález Dávila, Enrique
dc.date.accessioned2024-01-22T12:00:37Z
dc.date.available2024-01-22T12:00:37Z
dc.date.issued2023
dc.identifier.urihttp://riull.ull.es/xmlui/handle/915/35496
dc.description.abstractInfertility has become more common, with an increased exposure to toxic compounds including heavy metals (HM). Follicular fluid (FF) surrounds the developing oocyte in the ovary and can be analysed to assess metal content. The levels of twenty-two metals were measured in the FF of ninety-three females in a reproduction unit, and their influence on assisted reproduction technique (ART), were examined. The metals were determined by optical emission spectrophotometry. Low values of copper, zinc, aluminium, and calcium favour polycystic ovary syndrome. The relationships between the number of oocytes and metals: iron (rs=0.303; p=0.003) and calcium (rs=−0.276; p=0.007) are significant, as well as between the number of mature oocytes with iron (rs=0.319; p=0.002), calcium (rs=−0.307; p=0.003) and sodium (rs=−0.215; p=0.039) and are near to significance in the case of aluminium (rs=−0.198; p=0.057). In the group with a fertilisation rate ≤ 75%, 36% of the women presented calcium >176.62 mg/kg compared to the group with a fertilisation rate ≥ 75% where this percentage was only 10% (p=0.011). An excess of iron and calcium reduces the good quality embryo rate, and an excess of potassium impairs the blastocyst rate. If potassium is above 237.18 mg/kg and calcium is below 147.32 mg/kg, these conditions favour embryo implantation. Pregnancy is influenced by high potassium and low copper levels. Controlling exposure to toxic elements is recommended for all couples with reduced fertility or receiving an ART.es_ES
dc.language.isoenes_ES
dc.relation.ispartofseriesBiological Trace Element Research (2023) 201:5069–5082;
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleThe Influence of Follicular Fluid Metals on Assisted Reproduction Outcomees_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.identifier.doi10.1007/s12011-023-03578-3
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.subject.keywordMetales_ES
dc.subject.keywordFollicular fluides_ES
dc.subject.keywordARTes_ES
dc.subject.keywordEmbryo qualityes_ES
dc.subject.keywordPregnancyes_ES
dc.subject.keywordPolycystic ovary syndromees_ES
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones_ES


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