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dc.contributor.authorMorales González, Manuel José
dc.contributor.authorTrujillo, M.
dc.contributor.otherMedicina Interna, Dermatología y Psiquiatría
dc.date.accessioned2024-11-10T21:05:47Z
dc.date.available2024-11-10T21:05:47Z
dc.date.issued2007
dc.identifier.urihttp://riull.ull.es/xmlui/handle/915/40029
dc.description.abstractUrate oxidase is an endogenous enzyme found in most mammals but not in humans. Urate oxidase catalyzes the enzymatic oxidation of uric acid into allantoin, a metabolite that is 5–10 times more soluble in urine than uric acid. With complementary DNA technology it is possible to produce large quantities of the pure recombinant protein [1]. Rasburicase (RS), a recombinant form of urate oxidase, has been demonstrated to be superior to allopurinol in the control of uric acid production associated with acute leukemias and high-grade lymphomasen
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.relation.ispartofseriesAnnals of Oncology, 2007, 18 - 2
dc.rightsLicencia Creative Commons (Reconocimiento-No comercial-Sin obras derivadas 4.0 Internacional)
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es_ES
dc.titleRasburicase-induced fatal respiratory arrest?
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1093/annonc/mdl380
dc.subject.keywordrespiratory arrest
dc.subject.keywordRasburicase-induced


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