Consumo de medicamentos opioides en la provincia de Las Palmas durante el periodo 2016-2021

Abstract

En esta Tesis Doctoral se desarrolló una base de datos agregados y estandarizada mediante el sistema de clasificación de medicamentos anatómico-química-terapéutica (ATC) y la dosis diaria definida (DDD) que permitió un análisis de los patrones de consumo de opioides, ofreciendo una visión exhaustiva y comparativa en el ámbito provincial, insular y municipal, aspecto que resultó novedoso, y proporcionando herramientas para evaluar el impacto de factores locales en el uso de estos medicamentos.

This thesis developed an aggregated and standardized database using the Anatomical-Chemical-Therapeutic Classification (ATC) system and the Defined Daily Dose (DDD), which allowed the analysis of opioid use patterns, providing a comprehensive and comparative view at the provincial, island and municipal levels, which was a novel aspect, and providing tools to assess the impact of local factors on the use of these drugs. In all geographical areas analyzed, the most commonly used therapeutic subgroups were combinations of tramadol with non-opioid analgesics (N02AJ) and major synthetic opioids such as buprenorphine and fentanyl (N02AE), in line with international clinical guidelines.