RT info:eu-repo/semantics/bachelorThesis
T1 Estudio fitoquímico de endemismos canarios. Valorización de compuestos naturales. 
Artemisia thuscula: estudio fitoquímico y actividad antibacteriana
A1 Pegoraro, Clara
K1 Artemisia thuscula, Plantas Canarias
AB The utilization of herbs for medicinal purposes started in the early history ofmankind several thousand years ago. In this study, an endemic plant of Canary’s islandssuch as Artemisia thuscula Cav. (Asteraceae) was screened for its phytochemical andantibacterial properties. For this purpose, this plant was extracted in different solventsi.e. acetone, dichloromethane, methanol/water, hexane and ethyl acetate and withdifferent extraction methods such as maceration and sonication. The study involves thepreliminary screening, quantitative determination and the qualitative thin layerchromatographic separation of secondary metabolites from the root, bark, leaf andflower. Furthermore, a comparation of the phytochemical profile between wild plantsand the greenhouse ones took place.Phytochemical analysis unveiled the existence of different bioactive compoundsin these extracts. Also, thin layer chromatography and NMR analysis of certain activeextracts demonstrated the presence of common phytocompounds in the plant extracts.Antibacterial activity was determined against indicated bacterial strains(Escherichia coli, Staphylococcus aureus, Enterococcus faecalis, Pseudomonasaeruginosa, Campylobacter jejuni) among all extracts, steam greenhouse ones hadmaximum inhibition against S.aureus. The following essays showed that the responsibleof the antibacterial activity was one of the fractions that we separated in thechromatography column.Furthermore, some of roots, flower and leaf extracts showed several levels ofantimicrobial activity against at least, one of the bacterial lines.In conclusion, in future studies the compounds with the biological activity couldbe identified, isolated and pharmacologically tested.
YR 2019
FD 2019
LK http://hdl.handle.net/915/15980
UL http://hdl.handle.net/915/15980
LA es
DS Repositorio institucional de la Universidad de La Laguna
RD 22-nov-2024