RT info:eu-repo/semantics/bachelorThesis
T1 Estrategias en el diseño de fármacos
A1 Ramirez Reyes, Guillermo Francisco
K1 Computer-Aided Drug Discovery and Design (CADD), Tecnología farmacéutica
AB CADD methods have enabled us to optimize the design of drugs, reducing their costs and thetime spent through an ensemble of computational tools such as docking, QSAR, pharmacophoremodels and virtual screening while using, at the same time, databases to obtain the desiredcompounds. With these methods, we will find some possible “hits” compounds that, with thehelp of screening, will provide a lead compound that subsequently will be optimized and testedin vivo and in vitro experiments.Using computational tools has generated a greater knowledge about the interactions betweena ligand–receptor, as well as a greater precision in the selected compound and speed up thedevelopment of new drugs.Nowadays there is a large amount of new drugs in the market that have been discovered withthese methods and it is a standard protocol in drugs design strategies.
YR 2019
FD 2019
LK http://riull.ull.es/xmlui/handle/915/17524
UL http://riull.ull.es/xmlui/handle/915/17524
LA es
DS Repositorio institucional de la Universidad de La Laguna
RD 12-sep-2024