RT info:eu-repo/semantics/article T1 Osseointegration evaluation of ZrTi alloys with hydroxyapatite-zirconia-silver layer in pig's tibiae A1 Souto, Ricardo Manuel A1 Trincă, Lucia Carmen A1 Mareci, Daniel A1 Lozano Gorrín, Antonio Diego A1 Izquierdo Pérez, Javier A1 Burtan, Liviu A1 Motrescu, Iuliana A1 Vulpe, Vasile A1 Pavel, Geta A1 Strungaru, Stefan A1 Stoleriu, Iulian A1 Strat, Aurel Lulu A1 Solcan, Carmen K1 osseointegration K1 hydroxyapatite K1 zirconia K1 silver K1 Zr-Ti alloys K1 coating layer AB In this work we studied the main surface characteristics together with the in vivoosseointegration of three Zr-Ti alloys with hydroxyapatite-zirconia-silver (HAP-ZrO2-Ag) coating layer. The main purpose was to provide a quantitative evaluation andinterpretation from micro to nano scale of the processes involved in the osseointegrationof the HAP-ZrO2-Ag coated Zr-Ti specimens in a pig model. The surface characteristicswere studied by scanning electron microscopy (SEM), energy dispersive X-rayspectroscopy (EDX), and X-ray diffraction (XRD). After the insertion of the implantsinto pig tibia, the osseointegration was investigated by means of biochemical analysis aswell as bone histomorphometric and computed tomography measurements. The results ofthis in vivo study sustains that the capacity of the Zr-Ti specimens coated with HAPZrO2-Ag to promote osteogenesis is significant during the first month after implantationas compared with the control, being influenced by the interactions between bone tissueand HAP-ZrO2-Ag surfaces, but also by the chemical composition of the alloys. YR 2019 FD 2019 LK http://riull.ull.es/xmlui/handle/915/18947 UL http://riull.ull.es/xmlui/handle/915/18947 LA en DS Repositorio institucional de la Universidad de La Laguna RD 30-dic-2024