RT info:eu-repo/semantics/article
T1 In vitro corrosion resistance and in vivo osseointegration testing of new multifunctional beta-type quaternary TiMoZrTa alloys
A1 Souto, Ricardo Manuel
A1 Trincă, Lucia Carmen
A1 Mareci, Daniel
A1 Solcan, Carmen
A1 Fântânariu, Mircea
A1 Burtan, Liviu
A1 Vulpe, Vasile
A1 Hriţcu, Luminiţa
K1 multifunctional beta-type TiMoZrTa alloys
K1 in vitro corrosion resistance
K1 bone implants
K1 in vivo animal testing
K1 osseointegration
AB The present study explores the in vitro and in vivo responses of new multifunctionalquaternary beta-type TiMoZrTa alloys designed for biomedical implantation. Theelectrochemical resistance to corrosion of the alloys was investigated in vitro, using linearpotentiodynamic polarization (LPP) and electrochemical impedance spectroscopy (EIS) testsin acidified physiological saline solution at 37 oC. The pH was adjusted to 4.0 by adding lacticacid in order to simulate the hypoxia stress condition that may occur in the healing process offractures. The biomaterial alloys spontaneously formed a passivation oxide film on theirsurfaces, which remained stable for polarizations up to +1.0 VSCE, and became more resistantwith the increased amount of Ta in the alloy composition. The animal tests of the quaternaryTi-20Mo-7Zr-xTa alloys showed adequate biocompatibility as a tibial implant. Among them,the 15% Ta-alloy implant showed the best osseointegration according to the results of thebiochemical, histological and computed tomography characterizations, and can be consideredas a potential biomaterial with low elastic modulus (43.6 GPa).
YR 2020
FD 2020
LK http://riull.ull.es/xmlui/handle/915/18949
UL http://riull.ull.es/xmlui/handle/915/18949
LA en
DS Repositorio institucional de la Universidad de La Laguna
RD 22-dic-2024