RT info:eu-repo/semantics/article
T1 New Ti-6Al-2Nb-2Ta-1Mo alloy as implant biomaterial: in vitro corrosion and in vivo osseointegration evaluations
A1 Souto, Ricardo Manuel
A1 Trincă, Lucia Carmen
A1 Mareci, Daniel
A1 Solcan, Carmen
A1 Fântânariu, Mircea
A1 Burtan, Liviu
A1 Hriţcu, Luminiţa
A1 Chiruţă, Ciprian
A1 Fernández-Mérida, Luis
A1 Rodríguez Raposo, Raquel
A1 Santana, Juan José
K1 Ti-Al-Nb-Nb-Ta-Mo biomaterial
K1 in vitro corrosion testing
K1 in vivo osseointegration evaluation
K1 electrochemical impedance spectroscopy
K1 computed tomography
K1 rabbit animal model
AB Over the last decade, new titanium alloys are developed in different areas ofimplantology. The aim of this study was to characterize a new Ti-Al-Nb-Ta-Mo based alloy, withhigh potential for being used as a biomedical implant. The evaluation of Ti-6Al-2Nb-2Ta-1Mowas performed both in vitro (by monitoring its corrosion resistance in Hank’s Balanced SaltSolution, HBSS) and in vivo (by evaluating the osseointegration following rabbit tibiaimplantation), by comparison with titanium and Ti-6Al-7Nb alloy. Electrochemical impedancespectroscopy (EIS) data showed high impedance values for all titanium samples after 1 weekimmersion times in HBSS at 37 oC. According to EIS analysis, the corrosion resistance of the Ti-6Al-2Nb-2Ta-1Mo alloy immersed in HBSS was higher compared to the standard cp-Ti or withthe Ti-6Al-7Nb alloy. In addition, a higher degree of osseointegration was achieved by the Ti-6Al-2Nb-2Ta-1Mo alloy, thus probing that a higher resistance to electrochemical corrosionprovided enhanced protection to the implant surface against biodegradation, thus positivelyaffecting the qualitative and quantitative evolution of bone tissue repair.
YR 2020
FD 2020
LK http://riull.ull.es/xmlui/handle/915/18955
UL http://riull.ull.es/xmlui/handle/915/18955
LA en
DS Repositorio institucional de la Universidad de La Laguna
RD 12-nov-2024