RT info:eu-repo/semantics/article T1 New Ti-6Al-2Nb-2Ta-1Mo alloy as implant biomaterial: in vitro corrosion and in vivo osseointegration evaluations A1 Souto, Ricardo Manuel A1 Trincă, Lucia Carmen A1 Mareci, Daniel A1 Solcan, Carmen A1 Fântânariu, Mircea A1 Burtan, Liviu A1 Hriţcu, Luminiţa A1 Chiruţă, Ciprian A1 Fernández-Mérida, Luis A1 Rodríguez Raposo, Raquel A1 Santana, Juan José K1 Ti-Al-Nb-Nb-Ta-Mo biomaterial K1 in vitro corrosion testing K1 in vivo osseointegration evaluation K1 electrochemical impedance spectroscopy K1 computed tomography K1 rabbit animal model AB Over the last decade, new titanium alloys are developed in different areas ofimplantology. The aim of this study was to characterize a new Ti-Al-Nb-Ta-Mo based alloy, withhigh potential for being used as a biomedical implant. The evaluation of Ti-6Al-2Nb-2Ta-1Mowas performed both in vitro (by monitoring its corrosion resistance in Hank’s Balanced SaltSolution, HBSS) and in vivo (by evaluating the osseointegration following rabbit tibiaimplantation), by comparison with titanium and Ti-6Al-7Nb alloy. Electrochemical impedancespectroscopy (EIS) data showed high impedance values for all titanium samples after 1 weekimmersion times in HBSS at 37 oC. According to EIS analysis, the corrosion resistance of the Ti-6Al-2Nb-2Ta-1Mo alloy immersed in HBSS was higher compared to the standard cp-Ti or withthe Ti-6Al-7Nb alloy. In addition, a higher degree of osseointegration was achieved by the Ti-6Al-2Nb-2Ta-1Mo alloy, thus probing that a higher resistance to electrochemical corrosionprovided enhanced protection to the implant surface against biodegradation, thus positivelyaffecting the qualitative and quantitative evolution of bone tissue repair. YR 2020 FD 2020 LK http://riull.ull.es/xmlui/handle/915/18955 UL http://riull.ull.es/xmlui/handle/915/18955 LA en DS Repositorio institucional de la Universidad de La Laguna RD 20-abr-2024