RT info:eu-repo/semantics/bachelorThesis
T1 Papel del receptor de mineralocorticoides en la relación entre gluconeogénesis y síndrome metabólico.
A1 González Machín, Diana Elena
K1 Receptor de mineralocorticoides, Aldosterona, SGK1, Insulina, Síndrome Metabólico, Diabetes Mellitus, Hipertensión arterial, Hipertiroidismo, Gluconeogénesis, Sistema Renina-Angiotensina-Aldosterona
AB The Metabolic Syndrome is defined by different health organizations as the simultaneous presence in the same individual of factors such as high blood pressure, insulin resistance and obesity, among others, which predispose those who suffer from them to develop cardiovascular disease or diabetes mellitus. This syndrome has a high morbidity and mortality and associates to high health expenditure that concerns Public Health agencies. Therefore, research in search of therapies that allow to prevent, diagnose and treat this syndrome more effectively are of great relevance. In this search, several novel hypotheses have emerged, such as the possible relationship between the development of Metabolic Syndrome with elevated levels or the mineralocorticoid hormone aldosterone, its relation to other hormones such as glucocorticoids or thyroid hormones, its influence on controlling gluconeogenesis, or the role that the mineralocorticoid receptor plays in these processes.This work will analyze data currently available from various studies, in order to establish whether the mineralocorticoid receptor may or may not be a firm candidate as a therapeutic target in the treatment of the Metabolic Syndrome.
YR 2020
FD 2020
LK http://riull.ull.es/xmlui/handle/915/19339
UL http://riull.ull.es/xmlui/handle/915/19339
LA es
DS Repositorio institucional de la Universidad de La Laguna
RD 27-dic-2024