RT info:eu-repo/semantics/bachelorThesis T1 Características generales de los inhibidores de la bomba de protones y estudio de su utilización en dos farmacias comunitarias de Tenerife A1 González Ortiz, Alejandro K1 Inhibidores de la bomba de protones (IBP), Antiinflamatorios no esteroideos (AINEs), Gastroprotección, Polimedicados. AB In recent years, the unjustified use of proton pump inhibitors (PPI) in our country hasconsiderably increased. This thesis analyses, on one side, the general characteristicsof PPIs and, on the other side, their use in two community pharmacies in the island ofTenerife. Information collection was made through the elaboration of a survey directedto patients that were picking up a prescribed PPI. This method allowed to gatherinformation on the adequacy of PPI prescriptions to the indications made to thesepatients, as well as on a possible rebound effect and the degree of adherence ofpatients.Results show a high prescription level of PPIs in unjustified clinical cases and/or a highindefinite consumption, without a proper regular re-evaluation of its continuity. Thestudy highlights their high prescription as gastroprotective agents compared to drugsnot linked to NSAIDs. Similarly, a relevant rebound effect and low level of treatmentadherence were confirmed. Results reveal a need to raise awareness amonghealthcare professionals in order to check long term treatments and/or treatmentswhich are not suitable for PPIs. The implementation of a gradual reduction strategy inorder to avoid the rebound effect would be crucial too. YR 2020 FD 2020 LK http://riull.ull.es/xmlui/handle/915/20017 UL http://riull.ull.es/xmlui/handle/915/20017 LA es DS Repositorio institucional de la Universidad de La Laguna RD 26-dic-2024