RT info:eu-repo/semantics/bookPart
T1 Self-Healing Collagen-Based Hydrogel for Brain Injury Therapy
A1 de la Cruz, Raquel
A1 Díaz Díaz, David
K1 Brain therapy
K1 Central nervous system
K1 Collagen
K1 Hydrogel
K1 Regeneration
K1 terapia cerebral
K1 sistema nervioso central
K1 colágeno
K1 hidrogel
K1 regeneración
AB Hydrogels derived from biopolymers, also called biohydrogels, haveshown potential for brain injury therapy due to their tunable physical, chemical,and biological properties. Among different biohydrogels, those made from collagentype I are very promising candidates for the reparation of nervous tissues due to itsbiocompatibility, noncytotoxic properties, injectability, and self-healing ability.Moreover, although collagen does not naturally occur in the brain, it has beendemonstrated that collagen type I, which resides in the basal lamina of thesubventricular zone in adults, supports neural cell attachment, axonal growth, andcell proliferation due to its intrinsic content of specific cell-signaling domains. Thischapter summarizes the most relevant results obtained from both in vitro and in vivostudies using self-healing biohydrogels based on collagen type I as key componentin the field of neuroregeneration.
PB Springer
YR 2020
FD 2020
LK http://riull.ull.es/xmlui/handle/915/21312
UL http://riull.ull.es/xmlui/handle/915/21312
LA en
NO University of Regensburg
DS Repositorio institucional de la Universidad de La Laguna
RD 23-abr-2024