RT info:eu-repo/semantics/bachelorThesis
T1 Optimización de variables temporales y dosimétricas en algoritmos ultra-rápidos para estudios de gammagrafía ósea en un tomógrafo de emisión de fotón único (SPECT)
A1 Gey Segade, Mateo Alberto
AB The following work has been made by a student with the purpose of getting toknow an area which is quite an unknown for the physics students in the ULL. An areathat is going through a great growth due to the investments done for supporting it andthat is demanding more specialists every year. This work shows the procedure and theresults of a study made with various objectives, but also serves as an introduction to themedical physics and the nuclear medicine for those who do not know about thesesubjects, so anyone can read and enjoy it. Coming to the point, the main aim of the study is to ascertain in which mannerdoes the reduction of three parameters, two of them of the SPECT and the other one ofthe Activity introduced into the Jaszczak Phantom, independently affect to the quality ofthe resulting tomography. These parameters are the time in every stop of the SPECT’sdetectors, the angle of rotation of the detectors between each stop and the Activity ofradiopharmaceutical given to the patient before a SPECT. To achieve this goal, severaltests are done changing the parameters and obtaining different tomographyscorresponding to the various combinations of time, angle and dose ofradiopharmaceuticals. These tomographys are analyzed using the software ImageJ,creating ROIs in the valuable areas and measuring the mean of the signal per pixel andthe standard deviation. With these measures, two parameters are calculated in order toknow about the resolution of the SPECT (FTC) and the quality of the results (SNR).Then, by calculating another parameter relative to the tomographys’ quality (CNR) andusing the Rose criterion it is estimated whether or not the images are valid for theclinical diagnosis and also how the diminution of the mentioned parameters affect theresults. The other objective of the study is to verify the result of an article that states thata SPECT can be reduced from 13 to 4 minutes without loosing its diagnostic capacity. Since in the study shown in the article, they only argue they theory with the opinion ofseven doctor, it must be proven with empirical results in our study with the Rosecriterion. The decrease in time per test, in addition to assuming an improvement in patientcomfort, could also improve the quality of the result since in a short test the patientwould be less likely to move. With a significant reduction in the duration of theSPECTs, the number of tests that are carried out per day could also be increased and,being this a diagnostic test, the fact of being able to reduce the dose ofradiopharmaceutical that is supplied to the patient will also be an advantage because ofthe reduction of the risk of negative effects of the gamma radiation that is emitted insidethe body. A reduction in the dose used would also have as a consequence a decrease inthe economic costs of the SPECT.
YR 2021
FD 2021
LK http://riull.ull.es/xmlui/handle/915/25017
UL http://riull.ull.es/xmlui/handle/915/25017
LA es
DS Repositorio institucional de la Universidad de La Laguna
RD 26-nov-2024