RT info:eu-repo/semantics/bachelorThesis
T1 Avances en los sistemas transdérmicos para la administración de fármacos
A1 Nakhle Eid, María Pilar
A2 Grado En Farmacia
K1 Sistema transdérmico
K1 Absorción cutánea
K1 Microagujas
K1 Estrato córneo
K1 Promotores de la absorción
AB Transdermal systems are a type of pharmaceutical form that, when administered on the skin, allow the control of a constant drug release during a determined period of time.These types of systems are capable of maintaining constant drug levels in the systemic circulation, constituting an alternative administration method, with advantages over other routes of administration, such as oral or parenteral.It is essential to know the structure of the skin and its properties in order to administerdrugs topically. The stratum corneum of the skin represents the main effective barrier totopical and transdermal drug release. The transport through the skin plays a fundamentalrole in this type of systems, being very important the application of physical methods thatwill help to improve it, as well as to increase the permeability of the drug in the skin. Inaddition, it is possible to enhance drug penetration through the use of absorptionpromoters, among other physical methods such as heat, iontophoresis or sonophoresis.Throughout this work we show the trends found in these types of delivery systems in thelast 10 years, which concludes a further study of these pharmaceutical forms that are incontinuous progress. It is elaborated and determined by consulting different databasesand articles. However, they show certain drawbacks that make it a promising technique with limited use.
YR 2022
FD 2022
LK http://riull.ull.es/xmlui/handle/915/29968
UL http://riull.ull.es/xmlui/handle/915/29968
LA es
DS Repositorio institucional de la Universidad de La Laguna
RD 28-sep-2024