RT info:eu-repo/semantics/article T1 Metabolic syndrome after Roux-en-Y gastric bypass in patients with morbid obesity: Five years of follow-up, a before and after study. A1 Rodríguez Álvarez, Cristobalina A1 Acosta Torrecilla, Alfonso Orelve A1 Arias, Ángeles A1 González Dávila, Enrique Francisco K1 Laparoscopic gastric bypass K1 Bariatric surgery K1 Metabolic syndrome K1 Morbid obesity K1 Before-after study AB Background: Metabolic syndrome (MetS) is common among morbidly obese patients undergoing bariatric surgery. The aim of this study is to analyse prevalence and evolution of MetS in patients suffering from morbidobesity, before and after bariatric surgery, during a follow-up period of 5 years.Methods: A before-after study was carried out including 156 patients with MetS. The definition of metabolicsyndrome according to the Joint Interim Statement (JIS) definition was used. Demographic, as well as anthropometric, biochemical, and clinical analyses were assessed before, as well as 2 and 5 years after performinglaparoscopic Roux-en-Y gastric bypass (RYGB).Results: High BMI (100%), elevated blood pressure (78%) and low levels of high density lipoprotein (70%) werethe most prevalent criteria for MetS. The percentage of people with MetS decreased significantly to 48.9% at 2years and 24.1% at 5 years. The weight was also significantly reduced at 2 years, although at 5 years a reboundeffect is already observed. Percentage of total weight loss (%TWL) and excess BMI loss (%EBMIL) were.49.7 ± 19.4% and 68.2 ± 18.9%, respectively, at 2 years and 29.3 ± 11.6% and 62.0 ± 24.9 at 5 years,both presenting significant differences (p < 0.001).Conclusion: RYGB in obese patients is associated with a significant improvement of MetS and its comorbidities.Insufficient weight loss is the main factor related to the prevalence of MetS. SN 1743-9159 YR 2020 FD 2020 LK http://riull.ull.es/xmlui/handle/915/34824 UL http://riull.ull.es/xmlui/handle/915/34824 LA en DS Repositorio institucional de la Universidad de La Laguna RD 09-may-2024