RT info:eu-repo/semantics/article
T1 The Infuence of Follicular Fluid Metals on Assisted Reproduction Outcome
A1 Rodríguez Díaz, Rubí
A1 Blanes Zamora, Raquel
A1 Paz Montelongo, Soraya 
A1 Gómez Rodríguez, Jorge
A1 Rodríguez Fiestas, Sonsoles
A1 González Weller, Dailos
A1 Gutiérrez, Ángel J.
A1 Rubio, Carmen
A1 Hardisson, Arturo
A1 Niebla Canelo, Daniel
A1 Vega, Samuel
A1 González Dávila, Enrique
A2 Obstetricia y GinecologíaPediatría, Medicina Preventiva y Salud Pública, Toxicología y Medicina Legal y Forense y Parasitología
K1 Metal
K1 Follicular fluid
K1 Embryo quality
K1 Pregnancy
K1 Polycystic ovary syndrome
AB Infertility has become more common, with an increased exposure to toxic compounds including heavy metals (HM). Follicular fuid (FF) surrounds the developing oocyte in the ovary and can be analysed to assess metal content. The levels of twenty-twometals were measured in the FF of ninety-three females in a reproduction unit, and their infuence on assisted reproduction technique (ART), were examined. The metals were determined by optical emission spectrophotometry. Low values of copper,zinc, aluminium, and calcium favour polycystic ovary syndrome. The relationships between the number of oocytes and metals: iron (rs=0.303; p=0.003) and calcium (rs=−0.276; p=0.007) are signifcant, as well as between the number of mature oocytes with iron (rs=0.319; p=0.002), calcium (rs=−0.307; p=0.003) and sodium (rs=−0.215; p=0.039) and are near to signifcance in the case of aluminium (rs=−0.198; p=0.057). In the group with a fertilisation rate ≤ 75%, 36% of the women presented calcium >176.62 mg/kg compared to the group with a fertilisation rate ≥ 75% where this percentage was only 10% (p=0.011). An excess of iron and calcium reduces the good quality embryo rate, and an excess of potassium impairs the blastocyst rate. If potassium is above 237.18 mg/kg and calcium is below 147.32 mg/kg, these conditions favour embryo implantation. Pregnancy is infuenced by high potassium and low copper levels. Controlling exposure to toxic elements is recommended for allcouples with reduced fertility or receiving an ART.
YR 2023
FD 2023
LK http://riull.ull.es/xmlui/handle/915/34984
UL http://riull.ull.es/xmlui/handle/915/34984
LA 
DS Repositorio institucional de la Universidad de La Laguna
RD 17-may-2024