RT info:eu-repo/semantics/article
T1 Monitoring the rise of the SARS-CoV-2 lineage B.1.1.7 in Tenerife (Spain) since mid- December 2020.
A1 Valenzuela Fernández, Agustín
A1 Alcoba Florez, Julia
A1 Lorenzo- Salazar, Jose M.
A1 Gil Campesino, Helena
A1 Íñigo Campos, Antonio
A1 García Martínez de Artola, Diego
A1 García Olivares, Víctor
A1 Díez Gil, Óscar
A1 Ciuffeda, Laura
A1 González Montelongo, Rafaela
A1 Flores, Carlos
A2 Medicina Física y Farmacología
A2 Grupo "inmunología Celular y Viral".
K1 B.1.1.7
K1 20I/501Y.V1
K1 genomic surveillance
K1 spike mutations
K1 SGTF
AB Starting in December 2020, a sharp increase of COVID-19 cases occurred in Tenerifecompared to the rest of the Canary Islands (Spain). Because of the direct touristic connectionsbetween Tenerife and the UK, and the rapid transmission and dominance of the SARS-CoV-2B.1.1.7 variant of concern (VOC-202012/01) by the end of November 2020 in SouthEngland, here we measured the proportion of B.1.1.7 cases occurring between the 18th ofDecember 2020 and the 25th of February 2021. Out of the 2,091 COVID-19 positivenasopharyngeal swab samples assessed, 226 showed a spike gene target failure (SGTF).Subsequent viral genome sequencing further confirmed that 93.2% of them corresponded tothe B.1.1.7 lineage. Furthermore, a rapid increase in the proportion of SGTF variants wasdetected in up to 10.7% of positive cases during the Christmas season despite strictermeasures for containing the transmission were imposed in Tenerife in the period. Theseresults support the local transmission of SARS-CoV-2 B.1.1.7 lineage in Tenerife since lateDecember 2020 although it is not yet dominant.
YR 2021
FD 2021
LK http://riull.ull.es/xmlui/handle/915/35321
UL http://riull.ull.es/xmlui/handle/915/35321
LA en
NO medRxiv preprint doi: https://doi.org/10.1101/2021.03.14.21253535; this version posted March 15, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.It is made available under a CC-BY-NC-ND 4.0 International license .
DS Repositorio institucional de la Universidad de La Laguna
RD 11-jul-2024