RT info:eu-repo/semantics/article
T1 Membrane dynamics associated with viral infection.
A1 Valenzuela Fernández, Agustín
A1 Armas Rillo, Laura de
A1 Valera, María Soledad
A1 Marrero Hernández, Sara
A2 Medicina Física y Farmacología
A2 Grupo "Inmunología Celular y Viral".
AB Viral replication and spreading are fundamental events in the viral life cycle, accounting for the assembly and egression ofnascent virions, events that are directly associated with viral pathogenesis in target hosts. These processes occur in cellularcompartments that are modified by specialized viral proteins, causing a rearrangement of different cell membranes in infected cells and affecting the ER, mitochondria, Golgi apparatus, vesicles and endosomes, as well as processes such as autophagic membrane flux. In fact, the activation or inhibition of membrane trafficking and other related activities arefundamental to ensure the adequate replication and spreading of certain viruses. In this review, data will be presented thatsupport the key role of membrane dynamics in the viral cycle, especially in terms of the assembly, egression and infectionprocesses. By defining how viruses orchestrate these events it will be possible to understand how they successfully completetheir route of infection, establishing viral pathogenesis and provoking disease
YR 2015
FD 2015
LK http://riull.ull.es/xmlui/handle/915/35324
UL http://riull.ull.es/xmlui/handle/915/35324
LA en
DS Repositorio institucional de la Universidad de La Laguna
RD 29-jun-2024