RT info:eu-repo/semantics/article
T1 Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count.
A1 Valenzuela Fernández, Agustín
A1 Ruiz de León, María J.
A1 Jiménez Sousa, María A.
A1 Moreno, Santiago
A1 García, Marcial
A1 Gutiérrez Rivas, Mónica
A1 León, Agathe
A1 Montero Alonso, Marta
A1 González García, Juan
A1 Resino, Salvador
A1 Rallón, Norma
A1 Benito, José M.
A1 Vallejo, Alejandro
A2 Medicina Física y Farmacología
A2 Grupo "Inmunología Celular y Viral".
K1 Exosomes
K1 miRNAs
K1 HIV-1
K1 Elite controllers
K1 Immune activation
K1 Soluble biomarkers
AB Exosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137–0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = −0.649, p = 0.020), while no correlation between soluble biomarkers or cellular immune activation was found.
YR 2019
FD 2019
LK http://riull.ull.es/xmlui/handle/915/35337
UL http://riull.ull.es/xmlui/handle/915/35337
LA en
DS Repositorio institucional de la Universidad de La Laguna
RD 21-may-2024