RT info:eu-repo/semantics/article T1 Tracing the trajectories of SARS-CoV-2 variants of concern between December 2020 and September 2021 in the Canary Islands (Spain). A1 Valenzuela Fernández, Agustín A1 Ciuffreda, Laura A1 González Montelongo, Rafaela A1 Alcoba Florez, Julia A1 Gil Campesino, Helena A1 Rodríguez Pérez, Héctor A1 Íñigo Campos, Antonio A1 De Miguel Martínez, Isabel A1 Tosco Núñez, Tomás A1 Díez Gil, Óscar A1 Lorenzo Salazar, José M. A1 Flores, Carlos A2 Medicina Física y Farmacología A2 Grupo "inmunología Celular y Viral". AB Several variants of concern (VOCs) explain most of the Severe Acute Respiratory SyndromeCoronavirus 2 (SARS-CoV-2) epidemic waves in Europe. We aimed to dissect the spread of theSARS-CoV-2 VOCs in the Canary Islands (Spain) between December 2020 and September 2021at a micro-geographical level. We sequenced the viral genome of 8,224 respiratory samplescollected in the archipelago. We observed that Alpha (B.1.1.7) and Delta (B.1.617.2 and sublineages) were ubiquitously present in the islands, while Beta (B.1.351) and Gamma (P.1/P.1.1)had a heterogeneous distribution and were responsible for fewer and more controlled outbreaks.This work represents the largest effort for viral genomic surveillance in the Canary Islands so far,helping the public health bodies in decision-making throughout the pandemic. YR 2022 FD 2022 LK http://riull.ull.es/xmlui/handle/915/35352 UL http://riull.ull.es/xmlui/handle/915/35352 LA en NO medRxiv preprint doi: https://doi.org/10.1101/2022.02.26.22271544; this version posted May 12, 2022. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license . DS Repositorio institucional de la Universidad de La Laguna RD 23-may-2024