RT info:eu-repo/semantics/article
T1 A draft of the first genome sequence of Monkeypox virus associated with the multi-country outbreak in May 2022 from the Canary Islands, Spain.
A1 Valenzuela Fernández, Agustín
A1 Alcoba Florez, Julia
A1 Muñoz Barrera, Adrián
A1 Ciuffreda, Laura
A1 Rodríguez Pérez, Héctor
A1 Rubio Rodríguez, Luis A.
A1 Gil Campesino, Helena
A1 García Martínez de Artola, Diego
A1 Íñigo Campos, Antonio
A1 Díez Gil, Óscar
A1 González Montelongo, Rafaela
A1 Lorenzo-Salazar, José M.
A1 Flores, Carlos
A2 Medicina Física y Farmacología
A2 Grupo "inmunología Celular y Viral".
AB Monkeypox virus (MPXV) is a zoonotic Orthopoxvirus (OPV) (family Poxviridae) [1,2], endemic to West and Central Africa [3,4]. MPXV has been described in humans in Central and Western Africa (occurring mainly in tropical forest areas of Central Africa), as well as in other parts of the world [5-10]. Around the 13 May 2022, MPXV cases were reported in several countries and WHO declared communitary transmission of the virus [11]. Most reported cases so far have been presented through sexual health or other health services and have involved mainly men who have sex with men [12,13]. By early June 2022, 129 viral genomes had been deposited at GISAID with 46 SNPs shared by all these sequences and differing from the viral genome sequences from the 2018-2019 MPXV outbreak [14]. Preliminary data from polymerase chain reaction (PCR) assays indicate that these MPXV strains detected in Europe and other non-endemic areas belong to the West African clade [15].In Europe, several cases of MPXV infection have been associated with outbreaks in the Canary Islands and Spain [15]. A few sequences of the cases in Spain have been reported [16]. A total of 15 positive cases have been confirmed in the Canary Islands so far (10 more cases are under investigation, including 5 suspects and 5 probable cases as of June 13 2022) [17]. Here we describe the draft sequences of the first MPVX viral genome isolated in the Canary Islands the 31 May 2022 from a male adult patient with one week-onset mild symptoms (fever, odynophagia) and presenting at ER but not necessitating hospital admission.
YR 2022
FD 2022
LK http://riull.ull.es/xmlui/handle/915/35366
UL http://riull.ull.es/xmlui/handle/915/35366
LA en
NO Preprint  Virological - Monkeypox / Genome Reports.https://virological.org/t/a-draft-of-the-first-genome-sequence-of-monkeypox-virus-associated-with-the-multi-country-outbreak-in-may-2022-from-the-canary-islands-spain/864.
NO https://virological.org/t/a-draft-of-the-first-genome-sequence-of-monkeypox-virus-associated-with-the-multi-country-outbreak-in-may-2022-from-the-canary-islands-spain/864
DS Repositorio institucional de la Universidad de La Laguna
RD 21-may-2024