RT info:eu-repo/semantics/article
T1 Nanomaterials to combat SARS-CoV-2: Strategies to prevent, diagnose and treat COVID-19.
A1 Valenzuela Fernández, Agustín
A1 Cabrera Rodríguez, Romina
A1 Ciuffreda, Laura
A1 Pérez Yanes, Silvia
A1 Estévez Herrera,  Judith
A1 González Montelongo, Rafaela
A1 Alcoba Florez, Julia
A1 Trujillo González, Rodrigo Francisco
A1 García Martínez de Artola, Diego
A1 Gil Campesino, Helena
A1 Díez Gil, Óscar
A1 Lorenzo Salazar, José M.
A1 Flores, Carlos
A1 García Luis, Jonay
A2 Medicina Física y Farmacología
A2 Grupo "Inmunología Celular y Viral"
K1 nanoreagents
K1 personal protective equipment
K1 vaccines
K1 lipid nanoparticles
K1 modified mRNA
K1 recombinant proteins
K1 surveillance and diagnosis
K1 genome sequencing
AB The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)infection and the associated coronavirus disease 2019 (COVID-19),which severely affect the respiratory system and several organs andtissues, and may lead to death, have shown how science can respondwhen challenged by a global emergency, offering as a response a myriadof rapid technological developments. Development of vaccines atlightning speed is one of them. SARS-CoV-2 outbreaks have stressedhealthcare systems, questioning patients care by using standard nonadapted therapies and diagnostic tools. In this scenario, nanotechnologyhas offered new tools, techniques and opportunities for prevention, forrapid, accurate and sensitive diagnosis and treatment of COVID-19. Inthis review, we focus on the nanotechnological applications and nanobased materials (i.e., personal protective equipment) to combat SARSCoV-2 transmission, infection, organ damage and for the development ofnew tools for virosurveillance, diagnose and immune protection bymRNA and other nano-based vaccines. All the nano-based developedtools have allowed a historical, unprecedented, real time epidemiologicalsurveillance and diagnosis of SARS-CoV-2 infection, at community andinternational levels. The nano-based technology has help to predict anddetect how this Sarbecovirus is mutating and the severity of theassociated COVID-19 disease, thereby assisting the administration andpublic health services to make decisions and measures for preparednessagainst the emerging variants of SARS-CoV-2 and severe or lethalCOVID-19.
YR 2022
FD 2022
LK http://riull.ull.es/xmlui/handle/915/35367
UL http://riull.ull.es/xmlui/handle/915/35367
LA en
DS Repositorio institucional de la Universidad de La Laguna
RD 16-jun-2024