RT info:eu-repo/semantics/article
T1 Analyses of visuospatial and visuoperceptual errors as predictors of dementia in Parkinson¿s disease patients with subjective cognitive decline and mild cognitive impairment
A1 Nieto Barco, Antonieta
A1 Mata González, María
A1 Lorenzo, Jesús N.
A1 Barroso Ribal, José Domingo
K1 Movement disorders
K1 Neuropsychological
assessment
K1 Cognitive impairment
AB Objective: Subjective cognitive decline (SCD) and mild cognitive impairment (MCI) in Parkinson’s disease (PD) areconsidered as the risk factors for dementia (PDD). Posterior cortically based functions, such as visuospatial andvisuoperceptual (VS-VP) processing, have been described as predictors of PDD. However, no investigations havefocused on the qualitative analysis of the Judgment of Line Orientation Test (JLOT) and the Facial Recognition Test(FRT) in PD-SCD and PD-MCI. The aim of this work was to study the VS-VP errors in JLOT and FRT. Moreover,these variables are considered as predictors of PDD. Method: Forty-two PD patients and 19 controls were evaluatedwith a neuropsychological protocol. Patients were classified as PD-SCD and PD-MCI. Analyses of errors wereconducted following the procedure described by Ska, Poissant, and Joanette (1990). Follow-up assessment wasconducted to a mean of 7.5 years after the baseline. Results: PD-MCI patients showed a poor performance in JLOT andFRT total score and made a greater proportion of severe intraquadrant (QO2) and interquadrant errors (IQO). PD-SCDshowed a poor performance in FRT and made mild errors in JLOT. PD-MCI and QO2/IQO errors were independentrisk factors for PDD during the follow-up. Moreover, the combination of both PD-MCI diagnosis and QO2/IQO errorswas associated with a greater risk. Conclusions: PD-MCI patients presented a greater alteration in VS-VP processingobservable by the presence of severe misjudgments. PD-SCD patients also showed mild difficulties in VS-SP functions.Finally, QO2/IQO errors in PD-MCI are a useful predictor of PDD, more than PD-MCI diagnosis alone.
SN 1469-7661
YR 2021
FD 2021
LK http://riull.ull.es/xmlui/handle/915/35386
UL http://riull.ull.es/xmlui/handle/915/35386
LA en
DS Repositorio institucional de la Universidad de La Laguna
RD 24-nov-2024