RT info:eu-repo/semantics/article
T1 Depressive Symptoms in Friedreich Ataxia
A1 Nieto Barco, Antonieta
A1 Hernández Torres, Atteneri
A1 Pérez Flores, Javier
A1 Montón, Fernando
A2 Psicología ClínicaPsicobiología y Metodología
K1 Friedreich ataxia
K1 Cerebellum
K1 Depression
K1 Cognitive slowing
K1 Descriptive observational study
AB Background/Objective: Almost no attention has been paid to depression in Friedreich ataxia (FRDA), a highly disabling cerebellar degenerative disease. Our aim was to studythe presence and the profile of depressive symptoms in FRDA and their relationship withdemographic-disease variables and cognitive processing speed. Method: The study groupsconsisted of 57 patients with a diagnosis of FRDA. The Beck Depression Inventory-II was used toassess symptoms of depression. Speed of information processing was measured with a ChoiceReaction time task. Results: The mean BDI score for patients was significantly higher than themean score in the general population. Twenty one percent of participants scored in the moderate/severe range. A Cognitive-Affective score and a Somatic-Motivational score was calculatedfor each patient. Patients’ scores in both dimensions were significantly higher than the scoresin the general population. Demographic and disease variables were not related with symptomsof depression, except for severity of ataxia. Depressive symptoms predict cognitive reactiontimes. The greater proportion of variance was explained by the Cognitive-Affective dimension.Conclusions: Our data show that both somatic-motivational and cognitive affective symptomsof depression are frequent in individuals with FRDA. In addition, depressive symptoms mayinfluence cognition, especially, the cognitive and affective symptoms.
YR 2018
FD 2018
LK http://riull.ull.es/xmlui/handle/915/35402
UL http://riull.ull.es/xmlui/handle/915/35402
LA en
NO https://doi.org/10.1016/j.ijchp.2017.11.004
DS Repositorio institucional de la Universidad de La Laguna
RD 11-mar-2025