RT info:eu-repo/semantics/article T1 Transcranial Magnetic Stimulation for the Treatment of Cocaine Addiction: A Systematic Review A1 Torres Castaño, Alezandra A1 Rivero Santana, Amado A1 Perestelo Pérez, Lilisbeth A1 Duarte Díaz, Andrea A1 Toledo Chávarri, Ana A1 Ramos García, Vanesa A1 Álvarez Pérez, Yolanda A1 Cudeiro Mazaira, Javier A1 Padrón González, Iván A1 Serrano Pérez, Pedro K1 cocaine use disorder K1 craving K1 non-invasive brain stimulation K1 transcranial magnetic stimulation K1 systematic review AB Long-term cocaine use is associated with cognitive deficits and neuro-psychiatric pathologies. Repetitive transcranial magnetic stimulation (rTMS) is an emerging therapeutic strategy relatingto changes in brain activity. It stimulates the prefrontal cortex and is involved in inhibitory cognitivecontrol, decision making and care. This systematic review aims to evaluate and synthesize theevidence on the safety, effectiveness, and cost-effectiveness of rTMS for the treatment of cocaine addiction. A systematic review of the literature was carried out. The following electronic databases wereconsulted from inception to October 2020: MEDLINE, Embase, CINAHL, PsycINFO, Cochrane Central Register of Controlled Trials and Web of Science. Randomised controlled trials, non-randomisedcontrolled trials and case-series and full economic evaluations were included. Twelve studies wereincluded. No identified study reported data on cost-effectiveness. Significant results of the efficacy ofTMS have been observed in terms of the reduction of craving to consume and the number of dosesconsumed. No serious adverse effects have been observed. Despite the low quality of the studies, thefirst results were observed in terms of reduction of cocaine use and craving. In any case, this effect isconsidered moderate. Studies with larger sample sizes and longer follow-ups are required. SN 2077-0383 YR 2021 FD 2021 LK http://riull.ull.es/xmlui/handle/915/35571 UL http://riull.ull.es/xmlui/handle/915/35571 LA en DS Repositorio institucional de la Universidad de La Laguna RD 11-may-2024