RT info:eu-repo/semantics/masterThesis
T1 Computational studies on KRAS inhibitors using web based tools
A1 Diaz Oliva, Aitor
A2 Máster Universitario en Biomedicina Por la Universidad de la Laguna
AB In this work, a computational study of the KRAS protein with two of its inhibitors for the G12C variant, sotorasib and adagrasib, has been carried out.  Initially, the interaction between the KRAS G12C inhibitors and the protein was studied using publicly available software (Swissdock). Next the interactions were studied for the G12D, G12R and G13C variants of KRAS. In a effort to compare the results obtained with those given by professional software, these same interactions were studied using licensed software MOE. All the results obtained from the different software and the results obtained from the different KRAS variants were compared.
YR 2024
FD 2024
LK http://riull.ull.es/xmlui/handle/915/39498
UL http://riull.ull.es/xmlui/handle/915/39498
LA en
DS Repositorio institucional de la Universidad de La Laguna
RD 06-ene-2025