RT info:eu-repo/semantics/article T1 Rasburicase-induced fatal respiratory arrest? A1 Morales González, Manuel José A1 Trujillo, M. A2 Medicina InternaDermatología y Psiquiatría K1 respiratory arrest K1 Rasburicase-induced AB Urate oxidase is an endogenous enzyme found in mostmammals but not in humans. Urate oxidase catalyzes theenzymatic oxidation of uric acid into allantoin, a metabolitethat is 5–10 times more soluble in urine than uric acid. Withcomplementary DNA technology it is possible to produce largequantities of the pure recombinant protein [1]. Rasburicase(RS), a recombinant form of urate oxidase, has beendemonstrated to be superior to allopurinol in the control ofuric acid production associated with acute leukemias andhigh-grade lymphomas YR 2007 FD 2007 LK http://riull.ull.es/xmlui/handle/915/40029 UL http://riull.ull.es/xmlui/handle/915/40029 LA en DS Repositorio institucional de la Universidad de La Laguna RD 29-nov-2024