RT info:eu-repo/semantics/article
T1 Cost-effectiveness analysis of single-use duodenoscope applied to endoscopic retrograde cholangiopancreatography
A1 Castilla Rodríguez, Iván
A1 Nicolás-Pérez, David
A1 Gimeno-García, Antonio Zebenzuy
A1 Romero-García, Rafael Joaquín
A1 Hernandez-Guerra, Manuel
A2 Ingeniería Informática y de Sistemas
AB Secondary infections due to transmission via the duodenoscope have been reported in up to 3% of endoscopic retrograde cholangiopancreatographies. The use of single-use duodenoscopes has been suggested. We investigate the cost-effectiveness of these duodenoscopes use in cholangiopancreatography. Methods: A costeffectiveness analysis was implemented to compare the performance of cholangiopancreatographies with reusable duodenoscopes versus single-use duodenoscopes. Effectiveness was analysed by calculating quality-adjusted life years (QALY) from the perspective of the National Health System. Possibility of crossover from single-use to reusable duodenoscopes was considered. A willingness-to-pay of 25,000 euro/QALY was set, the incremental cost-effectiveness ratio (ICER) was calculated, and deterministic and probabilistic sensitivity analyses were performed. Results: Considering cholangiopancreatographies with single-use and reusable duodenoscopes at a cost of 2,900 and 1,333 euro, respectively, and a 10% rate of single-use duodenoscopes, ICER was greater than 3,000,000 euro/QALY. A lower single-use duodenoscope cost of 1,211 euro resulted in an ICER of 23,583 euro/QALY. When the unit cost of the single-use duodenoscope was 1,211 euro, a crossover rate of more than 9.5% made the use of the single-use duodenoscope inefficient. Conclusions: Singleuse duodenoscopes are cost-effective in a proportion of cholangiopancreatographies if its cost is reduced. Increased crossover rate makes single-use duodenoscope use not cost-effective.
YR 2024
FD 2024
LK http://riull.ull.es/xmlui/handle/915/43139
UL http://riull.ull.es/xmlui/handle/915/43139
LA en
DS Repositorio institucional de la Universidad de La Laguna
RD 13-nov-2025