RT info:eu-repo/semantics/bachelorThesis T1 Determinación fenotípica de Staphylococcus aureus resistente a meticilina. A1 Martín Bermudez, Ana K1 Staphylococcus aureus, Portador nasal, Resistencia a meticilina AB Staphylococcus aureus is a type of bacteria that causes a wide variety of infectionsin humans. The main reservoir is the human being, found in healthy carriers, especiallyin the nostrils, as well as in infected patients. Colonization can settle on the nasal mucosa,oropharynx, entire epidermis, chronic skin ulcers, wounds in the healing phase or in theurethra of indwelling catheter.Its main impact is due to the methicillin resistant strains (MRSA) that showresistance to all beta-lactams (penicillins, cephalosporins, carbapenems andmonobactams), and other antibiotics, which makes their treatment difficult. These strainswere limited to the hospital environment (MRSA-HA), being responsible for the majorityof nosocomial bacteremia. However, since the 1990s its epidemiology has changed untilit appears more and more in the community environment (MRSA-CO). Communitystrains can infect healthy individuals and present some toxins such as Panton-Valentineleukocidin (PVL) and phenol-soluble modulin (PSM) peptide toxins that give themgreater virulence than SARM-HA. That is why the rapid detection of the nasal carrierstate contributes to adequate control and treatment in order to reduce its transmission.The objective of this work is to determine the prevalence of CO-MRSA. For this,65 samples were collected from the nostrils of volunteers from the communityenvironment, for subsequent identification by biochemical tests and phenotypicdetermination of methicillin. YR 2020 FD 2020 LK http://riull.ull.es/xmlui/handle/915/19990 UL http://riull.ull.es/xmlui/handle/915/19990 LA es DS Repositorio institucional de la Universidad de La Laguna RD 29-abr-2024