RT info:eu-repo/semantics/article T1 Clinical and cost-effectiveness analysis of early detection of patients at nutrition risk during their hospital stay through the new screening method CIPA: a study protocol A1 Suárez Llanos, José Pablo A1 Benítez Brito, Néstor A1 Vallejo Torres, Laura A1 Delgado Brito, Irina A1 Rosat Rodrigo, Adriá A1 Hernández Carballo, Carolina A1 Ramallo Fariña, Yolanda A1 Pereyra García Castro, Francisca A1 Romero, Juan Carlos A1 Felipe Pérez, Nieves A1 García Niebla, Jennifer A1 Calderón Ledezma, Eduardo Mauricio A1 González Melián, Teresa de Jesús A1 Llorente Gómez de Segura, Ignacio A1 Barrera Gómez, Manuel Ángel A2 Ingeniería Química y Tecnología Farmacéutica K1 Nutrition assessment K1 Malnutrition K1 Inpatients K1 Body composition K1 Anthropometry K1 Cost-benefit analysis K1 Mass screening K1 Quality of life AB Background: Malnutrition is highly prevalent in hospitalized patients and results in a worsened clinical course aswell as an increased length of stay, mortality, and costs. Therefore, simple nutrition screening systems, such as CIPA(control of food intake, protein, anthropometry), may be implemented to facilitate the patient’s recovery process.The aim of this study is to evaluate the effectiveness and cost-effectiveness of implementing such screening tool ina tertiary hospital, consistent with the lack of similar, published studies on any hospital nutrition screening system.Methods: The present study is carried out as an open, controlled, randomized study on patients that wereadmitted to the Internal Medicine and the General and Digestive Surgery ward; the patients were randomized toeither a control or an intervention group (n = 824, thereof 412 patients in each of the two study arms). The controlgroup underwent usual inpatient clinical care, while the intervention group was evaluated with the CIPA screeningtool for early detection of malnutrition and treated accordingly.CIPA nutrition screening was performed upon hospital admission and classified positive when at least one of thefollowing parameters was met: 72 h food intake control < 50%, serum albumin < 3 g/dL, body mass index < 18.5 kg/m2(or mid-upper arm circumference ≤ 22.5 cm). In this case, the doctor decided on whether or not providing nutritionsupport.The following variables will be evaluated: hospital length of stay (primary endpoint), mortality, 3-month readmission,and in-hospital complications. Likewise, the quality of life questionnaires EQ-5D-5 L are being collected for all patientsat hospital admission, discharge, and 3 months post-discharge. Analysis of cost-effectiveness will be performed bymeasuring effectiveness in terms of quality-adjusted life years (QALYs). The cost per patient will be establishedby identifying health care resource utilization; cost-effectiveness will be determined through the incrementalcost-effectiveness ratio (ICER). We will calculate the incremental cost per QALY gained with respect to the intervention.Discussion: This ongoing trial aims to evaluate the cost-effectiveness of implementing the malnutritionscreening tool CIPA in a tertiary hospital. YR 2017 FD 2017 LK http://riull.ull.es/xmlui/handle/915/36116 UL http://riull.ull.es/xmlui/handle/915/36116 LA en DS Repositorio institucional de la Universidad de La Laguna RD 29-may-2024