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Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count.

dc.contributor.authorValenzuela Fernández, Agustín 
dc.contributor.authorRuiz de León, María J.
dc.contributor.authorJiménez Sousa, María A.
dc.contributor.authorMoreno, Santiago
dc.contributor.authorGarcía, Marcial
dc.contributor.authorGutiérrez Rivas, Mónica
dc.contributor.authorLeón, Agathe
dc.contributor.authorMontero Alonso, Marta
dc.contributor.authorGonzález García, Juan
dc.contributor.authorResino, Salvador
dc.contributor.authorRallón, Norma
dc.contributor.authorBenito, José M.
dc.contributor.authorVallejo, Alejandro
dc.contributor.otherMedicina Física y Farmacología
dc.contributor.otherGrupo "Inmunología Celular y Viral".
dc.date.accessioned2024-01-15T21:07:14Z
dc.date.available2024-01-15T21:07:14Z
dc.date.issued2019
dc.identifier.urihttp://riull.ull.es/xmlui/handle/915/35337
dc.description.abstractExosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137–0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = −0.649, p = 0.020), while no correlation between soluble biomarkers or cellular immune activation was found.en
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.relation.ispartofseriesJournal of Microbiology, Immunology and Infection, Volume 52, Issue 4, August 2019, Pages 667-671
dc.rightsLicencia Creative Commons (Reconocimiento-No comercial-Sin obras derivadas 4.0 Internacional)
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es_ES
dc.titleLower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count.en
dc.typeinfo:eu-repo/semantics/article
dc.identifier.doi10.1016/j.jmii.2018.07.007
dc.subject.keywordExosomesen
dc.subject.keywordmiRNAsen
dc.subject.keywordHIV-1en
dc.subject.keywordElite controllersen
dc.subject.keywordImmune activationen
dc.subject.keywordSoluble biomarkersen


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