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Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count.
dc.contributor.author | Valenzuela Fernández, Agustín | |
dc.contributor.author | Ruiz de León, María J. | |
dc.contributor.author | Jiménez Sousa, María A. | |
dc.contributor.author | Moreno, Santiago | |
dc.contributor.author | García, Marcial | |
dc.contributor.author | Gutiérrez Rivas, Mónica | |
dc.contributor.author | León, Agathe | |
dc.contributor.author | Montero Alonso, Marta | |
dc.contributor.author | González García, Juan | |
dc.contributor.author | Resino, Salvador | |
dc.contributor.author | Rallón, Norma | |
dc.contributor.author | Benito, José M. | |
dc.contributor.author | Vallejo, Alejandro | |
dc.contributor.other | Medicina Física y Farmacología | |
dc.contributor.other | Grupo "Inmunología Celular y Viral". | |
dc.date.accessioned | 2024-01-15T21:07:14Z | |
dc.date.available | 2024-01-15T21:07:14Z | |
dc.date.issued | 2019 | |
dc.identifier.uri | http://riull.ull.es/xmlui/handle/915/35337 | |
dc.description.abstract | Exosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137–0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = −0.649, p = 0.020), while no correlation between soluble biomarkers or cellular immune activation was found. | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | en | |
dc.relation.ispartofseries | Journal of Microbiology, Immunology and Infection, Volume 52, Issue 4, August 2019, Pages 667-671 | |
dc.rights | Licencia Creative Commons (Reconocimiento-No comercial-Sin obras derivadas 4.0 Internacional) | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es_ES | |
dc.title | Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count. | en |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | 10.1016/j.jmii.2018.07.007 | |
dc.subject.keyword | Exosomes | en |
dc.subject.keyword | miRNAs | en |
dc.subject.keyword | HIV-1 | en |
dc.subject.keyword | Elite controllers | en |
dc.subject.keyword | Immune activation | en |
dc.subject.keyword | Soluble biomarkers | en |